2-FORMYL-5-METHYL-PHENYLBORONIC ACID

2-FORMYL-5-METHYL-PHENYLBORONIC ACID - Names and Identifiers

Name	2-Formyl-5-methylphenylboronic acid
Synonyms	AKOS BRN-0672 2-Formyl-5-Methylphenylboronic 2-Formyl-5-methylphenylboronic acid 2-FORMYL-5-METHYL-PHENYLBORONIC ACID B-(2-formyl-5-methylphenyl)-Boronic acid boronic acid, B-(2-formyl-5-methylphenyl)- Boronic acid, B-(2-formyl-5-methylphenyl)- 2-Borono-4-methylbenzaldehyde, 2-Borono-p-tolualdehyde
CAS	40138-17-8
InChI	InChI=1/C8H9BO3/c1-6-2-3-7(5-10)8(4-6)9(11)12/h2-5,11-12H,1H3

2-FORMYL-5-METHYL-PHENYLBORONIC ACID - Physico-chemical Properties

Molecular Formula	C8H9BO3
Molar Mass	163.97
Density	1.20±0.1 g/cm3(Predicted)
Boling Point	375.3±52.0 °C(Predicted)
Flash Point	180.8°C
Vapor Presure	2.68E-06mmHg at 25°C
pKa	8.28±0.53(Predicted)
Storage Condition	Inert atmosphere,2-8°C
Refractive Index	1.54

2-FORMYL-5-METHYL-PHENYLBORONIC ACID - Risk and Safety

Hazard Symbols	Xi - Irritant
WGK Germany	3
Hazard Class	IRRITANT

2-FORMYL-5-METHYL-PHENYLBORONIC ACID - Introduction

Acid is an organic compound whose chemical formula is C8H9BO3. It is a powdery solid, colorless and odorless. The following is a detailed description of its nature, use, preparation and safety information:

Nature:
-Appearance: colorless powder
-Solubility: Soluble in some organic solvents such as methanol and chloroform, insoluble in water
-Melting point: about 140-150°C

Use:
Acid has a wide range of applications in organic synthesis and is often used as a ligand or reagent. It can undergo substitution reactions with other compounds for the synthesis of organic molecules with specific functions and structures. In particular, among the phenylboronic acid compounds, acidoprid can serve as an important biologically active precursor for the synthesis of small molecules.

Preparation Method:
The preparation of acid is usually carried out by the following steps:
1. react 2-methyl benzene boronic acid with acetyl chloride to generate 2-acetyl -5-methyl benzene boronic acid.
2. Under the condition, heat 2-acetyl -5-methyl benzene boronic acid to cause deacylation reaction to generate acid.

Safety Information:
No obvious harm to human health under normal use conditions. However, it is still a chemical and should be used with caution. Contact should avoid direct contact with skin and eyes, and ensure that the operation is carried out in a well-ventilated laboratory. Wear appropriate personal protective equipment such as gloves and safety glasses during handling. If inhaled or eaten, please seek medical attention.

Last Update：2024-04-10 22:29:15